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The spectrum of activity and pharmacology of combination beta-lactamase inhibitors, carbapenems, and monobactams will be reviewed here. The mechanisms of action and resistance and major adverse reactions of the beta-lactam antibiotics, issues related to penicillins, and cephalosporins are discussed separately.

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Acute pharyngitis is one of the most common conditions encountered in outpatient clinical practice. Most cases of acute pharyngitis are caused by respiratory viruses and are self-limited. However, symptoms of viral pharyngitis broadly overlap with pharyngitis caused by important treatable causes, such as group A Streptococcus (GAS) …Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odor, pruritus, and/or discomfort. The initial evaluation typically consists of a history, physical examination, and tests for specific infections, including sexually ...UpToDate: Industry-leading clinical decision support for enterprises. Medical information updates daily. Your care teams and leadership need the best evidence and clinical …UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care.

The clinical features of KD reflect widespread inflammation of primarily medium-sized muscular arteries. Diagnosis is based upon evidence of systemic inflammation (eg, fever) in association with signs of mucocutaneous inflammation. The characteristic bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, rash, extremity ...

Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating motor weakness involving ocular, bulbar, limb, and/or respiratory muscles. The weakness is due to an antibody-mediated, immunologic attack directed at proteins in the postsynaptic membrane of the neuromuscular junction (acetylcholine receptors or ...Hypertriglyceridemia is a common clinical condition most often identified in individuals who have had a lipid profile as part of cardiovascular risk assessment. (See "Screening for lipid disorders in adults", section on 'Choice of tests' and "Atherosclerotic cardiovascular disease risk assessment for primary prevention in adults: Our approach ...

Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF.INTRODUCTION. —. Acute rhinosinusitis (ARS) is defined as symptomatic inflammation of the nasal cavity and paranasal sinuses ( figure 1) lasting less than four weeks. The term "rhinosinusitis" is preferred to "sinusitis" since inflammation of the sinuses rarely occurs without concurrent inflammation of the nasal mucosa [ 1 ].The clinical approach to S. aureus bacteremia consists of careful history and physical examination, infectious disease consultation, and diagnostic evaluation including echocardiography and additional imaging as needed. History and physical examination. History – A careful history and physical examination is essential.Vaginal yeast infections (also called yeast vaginitis or vaginal candidiasis) are a common problem in women. The most common symptoms are itching and irritation of the vulva and around the opening of the vagina. Vaginal yeast infections usually occur as infrequent episodes, but can recur frequently and may cause chronic persistent symptoms.

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Apr 1, 2024 · For over a century, open appendectomy was the only standard treatment for appendicitis. Contemporary management of appendicitis is more sophisticated and nuanced: laparoscopic appendectomy has surpassed open appendectomy in usage, some patients with perforated appendicitis may benefit from initial antibiotic therapy followed by interval ...

Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials.American Association of Nurse Practitioners (AANP) UpToDate is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 051212. For each hour of participation with the UpToDate program, NPs can claim 1.0 contact hour.UpToDate offers clinical, drug, and patient content to support health professionals wherever care takes place. Learn about subscription options, expert editorial content, access at the point of care, and improved health outcomes with UpToDate.Jun 14, 2023 · EVALUATION AND DIAGNOSIS. The history and physical examination in patients presenting with a severely elevated blood pressure (or an acute rise in blood pressure over a previously normal baseline, even if the presenting pressure is <180/120 mmHg) should determine whether any of the following are present [ 1,5 ]: Acute head injury or trauma. Apr 5, 2024 ... Outline · - Respiratory/airborne transmission as primary route · - Minimal role of other person-to-person routes · - Viral shedding and period&...As the condition progresses, most people eventually have inflammation of the joints in the arms or legs. Less commonly, some people have inflammation of the hips and in the upper part of the spine. Joint symptoms — Joint-related symptoms typically include stiffness, pain, redness, warmth to the touch, and swelling.

Hyponatremia is a common electrolyte disorder that can have serious consequences. Learn how to diagnose and treat SIADH and reset osmostat, two causes of hyponatremia, with evidence-based guidelines.Jan 4, 2024 ... Outline · Constipation · - Osmotic laxatives · - Lubiprostone · - Guanylate cyclase agonists · - Sodium/hydrogen exchanger 3 (NHE...Clostridioides difficile infection (CDI) is one of the most common hospital-acquired (nosocomial) infections and is an increasingly frequent cause of morbidity and mortality among older adult hospitalized patients [ 1-3 ]. CDI is also increasingly diagnosed in younger patients and in the community.Acute pancreatitis is an acute inflammatory process of the pancreas. Overall mortality rates in acute pancreatitis are approximately 2 percent, but can be as high as 30 percent in patients with persistent organ failure (severe acute pancreatitis) [ 1 ]. This topic reviews the management of acute pancreatitis.UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care.

Hypoglycemia is the most common acute complication of glucose-lowering therapy and is associated with poor outcomes and quality of life in people with type 1 and type 2 diabetes. Hypoglycemia is more common among patients with type 1 diabetes than those with type 2 diabetes and is usually limited to patients with type 2 diabetes treated …PARENTERAL DRUGS. A variety of parenteral and oral antihypertensive drugs are available for use in these patients ( table 1) [ 1-7 ]. Few studies have compared these agents with one another, and all are tolerated reasonably well [ 8,9 ]. Thus, the drug of choice is often dictated by the type of hypertensive emergency and the local hospital ...

INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. It can also cause infection in the eye, skin, central nervous system, and/or visceral organs. This topic will review treatment and prevention of primary and recurrent HSV-1 infections in …Moved Permanently. The document has moved here.INTRODUCTION. The management of infective endocarditis (IE) includes prompt diagnosis, treatment with antimicrobial therapy, and in some cases of complicated IE, surgical management. Preventive measures including antimicrobial prophylaxis may reduce the risk of initial and recurrent IE for patients with relevant risk factors.Type 2 diabetes mellitus is a disorder that is known for disrupting the way your body uses glucose (sugar); it also causes other problems with the way your body stores and processes other forms of energy, including fat. All the cells in your body need sugar to work normally. Sugar gets into the cells with the help of a hormone called insulin.How do you make summer fun … for the kids AND yourself? Summer can be a stressful time for parents, so let’s share our best ideas for creating perfectly imperfect summer memories. ...The clinical presentation of adrenal insufficiency is variable, depending on whether the onset is acute, leading to adrenal crisis, or chronic, with symptoms that are insidious and vague. The diagnosis of adrenal insufficiency depends upon a critical level of clinical suspicion. Measurements of serum cortisol within three hours after wakening ...UpToDate contributors generally avoid use of NSAIDs, or use them with particular caution and at reduced doses, in older adults and patients (regardless of age) with existing or increased risk for cardiovascular, GI, or kidney disease. Concurrent gastroprotection (eg, a proton pump inhibitor) may be warranted.Immune thrombocytopenia (ITP, also called idiopathic thrombocytopenic purpura, immune thrombocytopenic purpura) is an acquired thrombocytopenia caused by autoantibodies against platelet antigens. It is one of the more common causes of thrombocytopenia in otherwise asymptomatic adults. Major diagnostic concerns in an …Severe sepsis in adults: Rapid overview of emergency management during first hour. Table 1. Securing the airway (if indicated), correcting hypoxemia, and establishing venous access for the early administration of fluids and antibiotics are priorities in the management of patients with sepsis and septic shock [ 3,4 ].

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UpToDate offers clinical, drug, and patient content to support health professionals wherever care takes place. Learn about subscription options, expert editorial content, access at the point of care, and improved health outcomes with UpToDate.

Jul 29, 2021 · Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. Acute pancreatitis is an acute inflammatory process of the pancreas. Overall mortality rates in acute pancreatitis are approximately 2 percent, but can be as high as 30 percent in patients with persistent organ failure (severe acute pancreatitis) [ 1 ]. This topic reviews the management of acute pancreatitis.Nausea, the unpleasant sensation of being about to vomit, can occur alone or can accompany vomiting (the forceful expulsion of gastric contents), dyspepsia, or other gastrointestinal symptoms. Nausea can occur without vomiting and, less commonly, vomiting occurs without nausea. Nausea is often more bothersome and disabling than …Management of insomnia requires a stepwise approach, beginning with attempts to eliminate, or at least minimize, the multiple contributing factors and comorbid illnesses that can interfere with optimal sleep. Insomnia often responds only partially to treatment of sleep-impairing influences, however, and many patients require treatment …UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, Obstetrics, Gynecology, and Women ...Choice of initial therapy in most patients — The three primary options for antihypertensive drug therapy in most patients include an ACE inhibitor (or ARB), a calcium channel blocker, or a thiazide diuretic (preferably a thiazide-like diuretic) [ 3 ].Vitamin D decreases bone loss and lowers the risk of fracture, especially in older adults. Along with calcium, vitamin D also helps to prevent and treat osteoporosis. Adequate vitamin D is needed for efficient calcium absorption. Vitamin D is normally made in the skin after exposure to sunlight. (See "Patient education: Vitamin D deficiency ...UpToDate is a trusted and evidence-based clinical resource tool that provides comprehensive and updated information on various medical topics. Log in to access the full content and features of UpToDate, or register for a free trial or subscription.As the condition progresses, most people eventually have inflammation of the joints in the arms or legs. Less commonly, some people have inflammation of the hips and in the upper part of the spine. Joint symptoms — Joint-related symptoms typically include stiffness, pain, redness, warmth to the touch, and swelling.

May 4, 2023 · The pharmacology, efficacy, contraindications, and side effects of metformin for the treatment of diabetes will be reviewed here. A general discussion of initial treatment of type 2 diabetes and the role of metformin in the prevention of diabetes, in the treatment of polycystic ovary syndrome, and in gestational diabetes are reviewed separately. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care.Google today introduced a new mobile management and security solution, Android Enterprise Essentials, which, despite its name, is actually aimed at small to medium-sized businesses...Aeromonas species grow at a range of temperatures, although they are isolated with increasing frequency during warmer months (May through October in the Northern hemisphere). Aeromonas species cause a wide spectrum of disease syndromes among warm- and cold-blooded animals, including fish, reptiles, amphibians, mammals, …Instagram:https://instagram. the shedd aquarium Symptoms and signs — Rhabdomyolysis is characterized clinically by the triad of myalgias, muscle weakness, and red to brown urine due to myoglobinuria [ 1 ]. Biochemically, several serum muscle enzymes are elevated, including CK. The degree of muscle pain and other symptoms varies widely. Most of the symptoms of rhabdomyolysis … airfare to punta cana from boston Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical radiographic syndrome of heterogeneous etiologies that are grouped together because of similar findings on neuroimaging studies. It is also often referred to as: To continue reading this article, you must sign in with your personal, hospital, or group practice subscription ... nse option chain Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF. wgn tv chicago UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide. For the best experience, we recommend using the most recent versions of Microsoft Edge, Mozilla® Firefox®, and Google Chrome™. UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide. For the best experience, we recommend using the most recent versions of Microsoft Edge, Mozilla® Firefox®, and Google Chrome™. train tickets amtrak Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or …Jan 25, 2023 · The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole). An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here. aero mexico UpToDate contributors generally avoid use of NSAIDs, or use them with particular caution and at reduced doses, in older adults and patients (regardless of age) with existing or increased risk for cardiovascular, GI, or kidney disease. Concurrent gastroprotection (eg, a proton pump inhibitor) may be warranted. flights to new york city from charlotte UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. Licensed to: UpToDate Marketing Professional Support Tag : [1102 - 104.224.14.69 - 24B2D16B6F - PR14 - UPT - 20240430-16:47:09UTC] - SM - MD - LG - XL LoadingIndices Commodities Currencies Stocks majic eraser Mar 28, 2024 ... Outline · Suboptimal response · - Adjunctive CBT · - Pharmacologic management · No response to SRI treatment · Partial response ... washington dc to boston ma For over 30 years, clinicians around the world have trusted the evidence-based content in the UpToDate® clinical decision support (CDS) system to help make crucial care decisions when it matters most. Founded by clinicians for clinicians, and backed by an expert editorial team in over 25 specialties, UpToDate provides the latest medical ... comic strip maker Aeromonas species grow at a range of temperatures, although they are isolated with increasing frequency during warmer months (May through October in the Northern hemisphere). Aeromonas species cause a wide spectrum of disease syndromes among warm- and cold-blooded animals, including fish, reptiles, amphibians, mammals, … malibu jack's louisville ky Jul 29, 2021 · Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. The management of bowel obstruction depends upon the etiology, severity, and location of the obstruction. The goals of initial management are to relieve discomfort and restore normal fluid volume, acid-base balance, and electrolytes. Bowel compromise (ischemia, necrosis, or perforation) and a surgically correctable cause of SBO (eg ... UpToDate is a trusted source of clinical information for health professionals. However, the page you are looking for can't be found. Try searching for a different topic or language.